ONE PROTOCOL
Complete protocol - one session each
3 Treatments
Hyperbaric Oxygen Therapy
Mitovit IHHT
NAD+ IV Infusion
One Protocol
All three at Reborne 9 Queen Anne Street, London
Cellular Optimisation Protocol - HBOT, Mitovit & NAD+
Three of the most clinically significant cellular therapies available, combined in one protocol. Each acts on mitochondrial function and cellular energy production through a distinct biological mechanism. Together, they produce a compounded effect on cellular repair, metabolic resilience, and biological restoration that no single therapy achieves alone.
This is medicine at the level of cellular biology - available now at Reborne at a limited introductory price.
Why This Combination
Three Mechanisms. One Biological Target.
Every cell in your body runs on ATP - the energy currency produced by mitochondria. As we age, mitochondrial function declines, ATP production falls, and the cellular repair, immune function, and metabolic processes that depend on it follow. The Cellular Optimisation Protocol targets this decline simultaneously from three distinct angles.
HBOT saturates tissues with dissolved oxygen, fuelling the ATP synthesis chain directly. Mitovit trains mitochondria to function more efficiently, stimulating new mitochondrial growth. NAD+ IV replenishes the coenzyme essential for every mitochondrial energy reaction - levels of which decline by up to 50% between ages 40 and 60. Compounded effect. One session.
The Protocol
What the Protocol Includes
Three clinically administered treatments, sequenced for maximum biological synergy.
Administered in our medical-grade hard-shell chamber at 1.5–2.0 ATA. At elevated pressure, oxygen dissolves directly into the blood plasma - reaching tissues and cells at concentrations up to ten times higher than normal. This saturates the mitochondrial oxygen supply chain, fuelling ATP synthesis and triggering cellular repair, anti-inflammatory signalling, and stem cell mobilisation.
Alternating cycles of reduced and enriched oxygen delivered through a comfortable mask - a controlled hypoxic-hyperoxic stimulus that triggers mitochondrial biogenesis. New, more efficient mitochondria are grown. Existing ones are conditioned. Mitovit produces a measurable improvement in mitochondrial density and function that compounds across repeated sessions.
NAD+ is the essential coenzyme for mitochondrial energy production - required for over 500 enzymatic reactions including the sirtuins that regulate DNA repair, metabolic efficiency, and biological ageing. IV delivery achieves therapeutic plasma concentrations that oral precursors cannot replicate. Administered last in the sequence, it ensures the mitochondria trained by HBOT and Mitovit have the substrate they need to respond and regenerate optimally.
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Treatment Experience
What to Expect
All three treatments are administered by the Reborne clinical team at our Marylebone clinic. The sequence is designed for both comfort and efficacy: HBOT is performed first to prime the oxygen environment, followed by Mitovit to deliver the mitochondrial training stimulus, then NAD+ IV to provide the metabolic substrate that sustains the cellular response.
Total visit time is approximately three to four hours. There is no significant preparation required. Most clients report a meaningful shift in energy, mental clarity, and physical ease within 24–48 hours of the protocol. There is no downtime.
Treatment Pathways
Who This Protocol Is For
The Cellular Optimisation Protocol is designed for adults who want to act at the level of cellular biology. It is appropriate across four clinical profiles.
For clients whose energy no longer matches their demands - whether from overwork, poor recovery, or the biological decline of mitochondrial efficiency with age. The protocol addresses the cellular root of fatigue rather than managing its surface symptoms.
For athletes and high-performers seeking accelerated recovery capacity, improved endurance, and enhanced metabolic efficiency. The combination produces an environment of accelerated tissue repair and elevated mitochondrial output that supports both physical and cognitive performance.
Mitochondrial dysfunction is one of the hallmarks of biological ageing. Declining NAD+, reduced mitochondrial biogenesis, and impaired cellular energy production are directly implicated in the acceleration of biological age. This protocol addresses all three simultaneously - making it one of the most clinically coherent single interventions for longevity-focused clients.
For clients recovering from illness, long-term viral infection, or immunological depletion. HBOT’s anti-inflammatory and repair effects, combined with NAD+’s role in immune cell metabolism and Mitovit’s cellular conditioning, provide a structured biological environment for recovery and immune restoration.
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