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Genetic Testing London
Precision Genomic Diagnostics
What Is Genetic Testing?
Genetic testing analyses your DNA to identify variations that may influence your health, disease risk, medication response, and optimal lifestyle choices. Unlike standard blood tests that measure current biomarkers, genetic testing reveals the inherited blueprint that shapes how your body functions - information that remains constant throughout your lifetime and provides actionable insights for truly personalised medicine.
At Reborne Longevity in London, we offer comprehensive genetic testing services ranging from whole exome sequencing (analysing all protein-coding genes) to targeted panels examining specific health domains. Our genetic diagnostics are interpreted by clinical experts and integrated into personalised longevity programmes, transforming genetic data into practical health strategies.
WHY IS GENETIC TESTING IMPORTANT FOR Healthspan?
Precision longevity medicine recognises that each individual has unique genetic predispositions affecting everything from cardiovascular risk to nutrient metabolism to medication response. Generic health advice and standard drug dosing ignore this biological individuality.
Genetic testing enables truly personalised care by revealing your inherited risk factors before disease develops, identifying how your body metabolises specific medications, determining optimal nutrition based on your genetic makeup, and uncovering predispositions that can be modified through targeted interventions. This is preventative medicine at its most fundamental level - working with your genetic blueprint rather than against it.
WHAT TYPES OF GENETIC TESTING DOES REBORNE LONGEVITY OFFER?
We offer a comprehensive range of genetic testing services, from broad whole exome analysis to targeted panels addressing specific clinical questions. The appropriate test depends on your health goals, family history, and the clinical questions we aim to answer.
Whole Exome Sequencing London - Comprehensive Genetic Analysis
What Is Whole Exome Sequencing?
Whole Exome Sequencing (WES) is the most comprehensive form of clinical genetic testing, analysing all approximately 20,000 protein-coding genes in the human genome. The exome represents roughly 1-2% of total DNA but contains approximately 85% of known disease-causing mutations, making it the most clinically actionable portion of the genome.
Unlike targeted gene panels that examine only specific genes, whole exome sequencing provides a comprehensive genetic portrait that can be interrogated for multiple purposes - from rare disease diagnosis to pharmacogenomic insights to carrier screening. The data from WES remains valuable throughout your lifetime as scientific understanding expands and new gene-disease associations are discovered.
What Does Whole Exome Sequencing Analyse?
Disease Risk Variants: Identification of pathogenic or likely pathogenic variants associated with hereditary conditions including cardiovascular disease, cancer predisposition syndromes, neurological conditions, and metabolic disorders.
Carrier Status: Detection of recessive gene variants that may be passed to children, relevant for family planning and understanding inherited conditions.
Pharmacogenomic Variants: Genetic variations affecting drug metabolism, efficacy, and adverse reaction risk across multiple medication classes.
Actionable Incidental Findings: Clinically significant findings in genes recommended for reporting by medical guidelines, even when not the primary indication for testing.
Who Should Consider Whole Exome Sequencing?
Whole exome sequencing is particularly valuable for:
Proactive Health Optimisation: Individuals seeking the most comprehensive genetic insight to guide preventative strategies and personalised longevity protocols.
Complex Family History: Those with multiple conditions in their family where targeted panels may miss relevant variants.
Diagnostic Odyssey: Patients with unexplained symptoms where previous targeted testing has been uninformative.
Future-Proofing: WES data can be reanalysed as new gene discoveries are made, providing ongoing value without repeat testing.
How Does the Whole Exome Sequencing Process Work?
Step 1 - Consultation: Pre-test genetic counselling to discuss goals, family history, and implications of testing.
Step 2 - Sample Collection: Simple blood draw or saliva sample collected at our London clinic.
Step 3 - Laboratory Analysis: Sequencing performed by an accredited clinical genomics laboratory using next-generation sequencing technology.
Step 4 - Clinical Interpretation: Expert analysis of variants with classification according to international guidelines (ACMG).
Step 5 - Results Integration: Findings discussed in detail and incorporated into your personalised longevity programme with actionable recommendations.
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