£300
Per session
Mitovit IHHT — Intermittent Hypoxic-Hyperoxic Training
The most direct and evidence-supported method available for training your mitochondria — the cellular engines that produce all the energy your body runs on — without moving a muscle.
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Mitovit IHHT uses precisely controlled alternating exposures to low-oxygen and oxygen-enriched air to trigger a powerful cascade of mitochondrial and cellular adaptations. You recline comfortably, breathe through a clinical-grade mask, and allow the system’s real-time adaptive technology to do the work. Over five thousand peer-reviewed studies support the clinical applications of intermittent hypoxic training.
Why Mitochondria Are the Foundation
Your Energy, Your Age, Your Health — All Mitochondrial
Every cell in your body contains mitochondria — the organelles responsible for converting oxygen and nutrients into ATP: the molecular fuel that powers every biological process. Your brain, heart, and skeletal muscle are among the most mitochondria-dense tissues, and among the most vulnerable to mitochondrial decline.
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As we age, damaged mitochondria accumulate, ATP production falls, oxidative stress increases, and the cell’s ability to repair itself diminishes. Mitochondrial decline is now recognised as one of the primary hallmarks of ageing — an upstream driver of fatigue, cognitive decline, cardiovascular disease, and metabolic dysfunction. IHHT is the most effective known stimulus for reversing it.
​Medical Therapy
How the Session Works
You recline on a treatment couch, fitted with the Mitovit clinical breathing mask and pulse oximeters that continuously monitor your blood oxygen saturation in real time. The system then delivers a controlled sequence of hypoxic and hyperoxic air — automatically adjusting at every moment based on your individual physiological response.
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Each session cycles between altitude air (9–18% Oâ‚‚, triggering cellular stress signals and mitochondrial renewal) and oxygen-enriched recovery air (30% Oâ‚‚, until your SpOâ‚‚ returns to 99%). This cycle repeats 4–8 times across approximately 40 minutes. HRV is measured throughout, and a full data output is produced at the end of every session.
Treatment Experience
What to Expect
A Mitovit session requires nothing of you physically. Your first session begins with a gentle automated hypoxia calibration test that determines your individual threshold and personalises the oxygen parameters for all subsequent sessions. After that you simply arrive, recline, and breathe.
You may notice a mild awareness of slightly reduced or slightly enriched air — nothing more. Most clients find the experience deeply restful and close their eyes for the duration. There is no downtime. Most clients report feeling energised and clear-headed immediately afterwards. Course pricing is available for clients committing to 10 or more sessions.
Treatment Pathways
Treatment Pathways
Mitovit IHHT is relevant across a broad range of clinical profiles. Mitochondria are foundational to virtually every aspect of physiological function — interventions that genuinely improve mitochondrial health produce benefits that extend across multiple systems simultaneously.
IHHT addresses two of the updated hallmarks of ageing — mitochondrial dysfunction and impaired mitophagy — through a single non-invasive protocol. Published research has demonstrated measurable improvements in biological age markers following structured IHHT courses. At Reborne, Mitovit is integrated with TPE, Red Light Therapy, and diagnostic programmes for clients pursuing comprehensive biological age optimisation.
IHHT directly stimulates the production of new, high-functioning mitochondria — addressing the probable biological root of persistent fatigue at the cellular level. A 2024 controlled trial in the Journal of Cachexia, Sarcopenia and Muscle demonstrated significantly improved functional capacity and quality of life in long COVID patients compared to standard rehabilitation alone.
IHHT has a substantial RCT evidence base in cardiac rehabilitation, producing measurable improvements in VOâ‚‚ max, cardiac efficiency, blood pressure, lipid profiles, and insulin sensitivity. In cardiac rehabilitation settings, IHHT has been shown to outperform conventional exercise programmes in improving functional capacity in patients with coronary artery disease.
IHHT has demonstrated significant improvements in cognitive function across multiple RCTs, including in patients aged up to 92. Mechanisms include enhanced cerebral blood flow, reduced neuroinflammation, and upregulation of neurotrophic factors including BDNF. One of the most evidence-supported non-pharmacological options available for cognitive optimisation and proactive neuroprotection.
Mitovit IHHT delivers the core physiological adaptations of altitude training — erythropoiesis, capillary density, mitochondrial biogenesis — in a 40-minute reclined session, without logistical demands or muscle catabolism. Used in Bryan Johnson’s Blueprint longevity protocol as a core cellular performance strategy.
Treatment Experience
Is Mitovit IHHT Right for Me?
Mitovit IHHT is well-tolerated across a wide range of ages and health backgrounds — published trials have demonstrated its safety and efficacy in patients aged up to 92, including those with coronary artery disease, type 2 diabetes, COPD, and long COVID. The adaptive biofeedback technology ensures the hypoxic load is never delivered beyond what your individual physiology can safely tolerate.