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Pharmacogenomic Testing London
Personalised Medication Guidance
What Is Pharmacogenomic Testing?
Pharmacogenomics (PGx) is the study of how genetic variations affect individual responses to medications. Pharmacogenomic testing analyses genes encoding drug-metabolising enzymes, drug transporters, and drug targets to predict how you will respond to specific medications - including efficacy, optimal dosing, and risk of adverse reactions.
Standard drug dosing assumes everyone metabolises medications the same way - but genetic variations mean that a standard dose may be ineffective for some patients (ultra-rapid metabolisers) while causing toxicity in others (poor metabolisers). Pharmacogenomic testing enables precision prescribing, selecting the right medication at the right dose for your genetic profile.
What Medications Does Pharmacogenomic Testing Cover?
Hair Loss Treatments (Trichology): Genetic variants affecting metabolism of finasteride, minoxidil response, and other hair restoration medications. Helps predict efficacy and potential side effect risk.
Cardiovascular Medications: Statins (risk of myopathy), anticoagulants (warfarin dosing), antiplatelets (clopidogrel activation), beta-blockers, and antihypertensives.
Psychiatric Medications: Antidepressants (SSRIs, SNRIs, tricyclics), anxiolytics, antipsychotics, and mood stabilisers. Critical for mental health treatment optimisation.
Pain Medications: Opioid metabolism (codeine, tramadol), NSAIDs, and other analgesics.
Hormone Therapies: Oestrogen metabolism, testosterone therapy response, thyroid medication dosing, and contraceptive considerations.
Anaesthetics: Genetic variants affecting anaesthetic metabolism and malignant hyperthermia risk.
How Does Pharmacogenomic Testing Improve Treatment?
Avoid Adverse Reactions: Identify patients at high risk of serious side effects before prescribing.
Optimise Dosing: Determine appropriate starting doses based on metaboliser status rather than trial-and-error.
Improve Efficacy: Select medications most likely to work for your genetic profile.
Reduce Time to Effective Treatment: Avoid months of failed medication trials by selecting appropriately from the start.
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