Metabolic & Cardiovascular Optimisation
Led by Professor Andrew J. Krentz - a globally recognised leader in cardiometabolic medicine and preventive endocrinology
Definition: Metabolic & Cardiovascular Optimisation
Metabolic & Cardiovascular Optimisation is a proactive, science-led program designed to improve how your body regulates energy, blood sugar, fat metabolism, and heart health. At Reborne, we use advanced diagnostics and personalised interventions to:
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Detect early signs of metabolic or cardiovascular risk
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Enhance circulation, insulin sensitivity, and energy balance
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Reduce long-term risk of conditions like diabetes, heart disease, and stroke
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Support peak performance, vitality, and healthy aging
Led by expert clinicians, this program helps you take control of your internal health — long before symptoms appear.
Clients who:
✅ Are concerned about early signs of metabolic dysfunction — e.g., fatigue, weight gain, abdominal fat, poor glucose tolerance, or high blood pressure
✅ Have a family history of diabetes, cardiovascular disease, or stroke
✅ Have already been diagnosed with conditions such as:
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Prediabetes or type 2 diabetes
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High cholesterol or dyslipidaemia
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Hypertension or borderline high blood pressure
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Insulin resistance or PCOS (in women)
✅ Are interested in reducing cardiovascular risk proactively through expert guidance
✅ Want to integrate cutting-edge diagnostics with personalized prevention strategies
✅ Are high-performance professionals or athletes seeking to optimize metabolic efficiency and long-term energy output
Who Is Suitable For This Program?
Each client undergoes a comprehensive consultation and review with Professor Krentz, with tailored recommendations based on advanced diagnostic testing and clinical insights. The program may include:
🔬 Advanced biomarker screening, including fasting insulin, adiponectin, lipoprotein subfractions, inflammatory markers, and glycation endpoints
🧬 Genetic and epigenetic risk analysis (if indicated)
🫀 Cardiovascular functional testing and arterial stiffness assessment
🍽️ Metabolic load evaluation: glucose tolerance, insulin sensitivity profiling, and nutrient response mapping
📈 Ongoing tracking of weight composition, visceral fat, and metabolic age
💊 Personalized pharmacologic or nutraceutical interventions
🥗 Lifestyle and nutritional optimisation — informed by clinical evidence
📋 Referral for additional imaging (e.g. coronary calcium scoring) or cardiac review where needed
What to Expect in Your Program
Professor Krentz combines clinical precision with a forward-thinking view of longevity. His philosophy is rooted in early detection, comprehensive profiling, and sustainable intervention, empowering patients to extend their healthspan, not just treat disease.
His expertise is particularly valuable for clients who are:
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Not receiving adequate insight or strategy through standard GP or endocrinology channels
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Experiencing complex or multi-system symptoms with no clear diagnosis
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Seeking elite-tier longevity planning with metabolic health as a core focus
Professor Andrew J. Krentz’s Clinical Philosophy
Metabolic dysfunction is one of the most silent accelerators of biological aging — often beginning years before symptoms arise. Early detection and targeted intervention can dramatically improve your energy, cognitive clarity, immune resilience, and future disease risk.
At Reborne, Professor Krentz ensures your metabolic and cardiovascular health are not just monitored — but mastered.
Why It Matters
Your journey starts with a consultation and medical review overseen by Professor Krentz and our in-house longevity physicians. From there, a phased investigation and treatment plan is built around your biology, lifestyle, and long-term goals.
How to Begin
