Mitovit: The Oxygen-Based Therapy Backed by Nobel-Winning Science

When it comes to longevity, few names spark as much conversation as Bryan Johnson, who has built a global following around his ambitious quest to slow down ageing. One of the tools he just started using is intermittent hypoxia–hyperoxia therapy (IHHT)—the very same treatment we offer at Reborne Longevity through Mitovit.

IHHT is sometimes described as “altitude training for your cells.” By alternating short bursts of low oxygen (hypoxia) with periods of high oxygen (hyperoxia), the therapy mimics the effects of training at high altitude and pushes your cells to adapt and grow stronger.

The science behind it is profound. In 2019, the Nobel Prize in Medicine was awarded to researchers who discovered the molecular mechanisms that allow our cells to sense and respond to oxygen levels. Mitovit applies this breakthrough knowledge in a clinical setting, harnessing your body’s natural adaptation pathways to regenerate mitochondria—the tiny powerhouses of our cells.

So what does this mean for health and longevity? A growing body of research shows that controlled, intermittent hypoxia can trigger positive adaptations in the body. Studies published in the Journal of Physiology highlight how hypoxia activates key cellular pathways such as HIFs, Nrf2, and NFkB, which regulate oxygen supply, antioxidant defences, and inflammation. Clinical evidence also points to benefits in areas like cardiac rehabilitation, metabolic health, and even cognitive performance in older adults.

At Reborne Longevity, we see these effects come to life every day. Mitovit helps clients improve circulation, reduce inflammation, support more restorative sleep, enhance stress resilience, and sharpen cognitive performance. For others, it’s about building aerobic capacity and energy reserves that serve as powerful predictors of long-term health.

Mitovit can be booked as a single therapy or as part of a more comprehensive programme at Reborne Longevity. Either way, the goal is the same: to strengthen your health at the cellular level today while building resilience for the years ahead.